Anatomy of protein disorder, flexibility and disease-related mutations
نویسندگان
چکیده
منابع مشابه
Anatomy of protein disorder, flexibility and disease-related mutations
Integration of protein structural information with human genetic variation and pathogenic mutations is essential to understand molecular mechanisms associated with the effects of polymorphisms on protein interactions and cellular processes. We investigate occurrences of non-synonymous SNPs in ordered and disordered protein regions by systematic mapping of common variants and disease-related SNP...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Biosciences
سال: 2015
ISSN: 2296-889X
DOI: 10.3389/fmolb.2015.00047